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Non-Animal Origin Eye Drop Grade Sodium Hyaluronate Powder

Eye drop grade sodium hyaluronate is specifically designed for ophthalmic preparations such as eye drops. It is produced using advanced bio-fermentation technology, eliminating the risks of viral contamination, allergens, and batch-to-batch variations associated with animal tissue extraction, thereby meeting the stringent requirements of modern ophthalmic care for safety and stability.

    Product specification

    Brand Name MHW CHEM
    Model Number MHW-FU-2026045
    Product Name Sodium Hyaluronate
    Chemical Formula (C14H20NNaO11)n
    Chemical
    Structure
    CAS No. 9067-32-7
    Appearance White, fine powder
    Assay ≥99.5%
    Solubility Soluble in water
    Heavy metals ≤10ppm
    Protein ≤0.1%
    Bacterial endotoxins ≤0.5IU/mg
    Source Microbial fermentation

    Core Advantages

    1. Pure Source, Complete Peace of Mind
    Sodium hyaluronate is produced by microbial fermentation with no contact with animal tissues. It is suitable for people with long-term eye care needs, such as dry eye syndrome, contact lens wear, and post-operative care.

    2. High Standards for Eye Drop Grade
    Sodium hyaluronate complies with eye drop grade standards, with quality indicators superior to cosmetic or food grade. Molecular weight is controllable, and proteins, nucleic acids, heavy metals, and microorganisms are strictly controlled, ensuring no irritation or sensitization.

    3. Excellent Biocompatibility and Water-Retention Capacity
    The structure of sodium hyaluronate is identical to that naturally found in the human body, offering outstanding viscoelasticity and water retention. It forms a stable hydrated film on the corneal surface, prolongs tear film breakup time, and alleviates dryness and foreign body sensation.

    4. Superior Rheological Properties
    Once reconstituted, sodium hyaluronate exhibits pseudoplastic fluid behavior — high viscosity at rest for firm retention on the ocular surface, and decreased viscosity during blinking without affecting vision. It balances effective residence time with comfortable eye drop experience.

    5. High Batch-to-Batch Consistency
    The fermentation process is mature, allowing precise control over molecular weight, viscosity, moisture, pH, and other key parameters. Without the fluctuations seen in animal extraction methods, it provides formulation manufacturers with a highly reproducible raw material guarantee.

    Why Choose Non-Animal Origin?

    Although traditional animal-derived sodium hyaluronate (e.g., extracted from rooster combs) has a lower cost, it poses several potential risks:

    ▪ Possible residues of avian viruses, prions, and other pathogens

    ▪ Higher levels of protein and nucleic acid residues, which may trigger allergies or immune responses

    ▪ Significant variability in molecular weight and quality across different animals and batches

    ▪ Does not meet the needs of those who prefer vegan or animal-free ingredients

    Non-animal fermented HA perfectly avoids the above issues and has become the preferred raw material for leading eye drop brands in Europe, the US, and China.

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