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Eye Drop Grade Sodium Hyaluronate for Ophthalmic Preparations

Eye drop grade sodium hyaluronate refers to high-purity sodium hyaluronate that meets the quality standards for ophthalmic preparations. It is typically produced through microbial fermentation and is not derived from animals. This grade of product has strict requirements regarding molecular weight distribution, purity, aseptic control, endotoxin content, and biocompatibility, making it suitable for formulation systems that come into direct contact with the ocular surface.

    Product specification

    Brand Name MHW CHEM
    Model Number MHW-FU-2025009
    Product Name Sodium Hyaluronate
    Chemical Formula  (C14H20NNaO11)n
    Chemical
    Structure
     
    CAS No. 9067-32-7
    Appearance White, fine powder
    Assay ≥99.5%
    Application Ophthalmic care
    Function Moisturizes and lubricates the ocular surface, relieving dry eye discomfort.
    Solubility Soluble in water
    Heavy metals ≤10ppm
    Protein ≤0.1%
    Bacterial endotoxins ≤0.5IU/mg
    Source Microbial fermentation
    Packaging 100g/foil bag, 1kg/foil bag or as per customer’s request.
    Shelf life 2 years
    Storage conditions Avoid light, refrigerate 2℃~10℃, seal container.

    Application

    1. Artificial Tears and Lubricating Eye Drops: Eye drop-grade sodium hyaluronate possesses excellent water-retention and viscoelastic properties, forming a stable hydration protective layer on the ocular surface to help maintain tear film stability. It is commonly used in artificial tears and lubricating eye drops to relieve dry eye and discomfort.

    2. Ocular Surface Protection and Repair Formulations: Sodium hyaluronate exhibits good biocompatibility with ocular surface tissues, providing lubrication and protection, reducing blinking friction, and aiding in the stabilization of the ocular surface environment and the repair of minor damage. It is suitable for ocular surface care and postoperative care formulations.

    3. Drug Delivery and Formulation Performance Optimization: Due to its excellent adhesion and rheological properties, eye drop-grade sodium hyaluronate helps prolong the residence time of formulations on the ocular surface, enhancing the persistence of action of active ingredients and improving the comfort of eye drops.

    4. Preservative-free or low-irritant ophthalmic systems: Eye drop grade sodium hyaluronate is suitable for preservative-free or low-irritant ophthalmic formulations and can be used in single-dose or multi-dose formulations to meet the safety requirements of long-term or high-frequency use and people with sensitive eyes.

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