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Injection Grade Hyaluronic Acid Powder Microbial Fermentation Production
Product specification
| Brand Name | MHW CHEM |
| Model Number | MHW-FU-2026039 |
| Product Name | Hyaluronic Acid |
| Chemical Formula | (C14H21NO11)n |
| Chemical Structure |
|
| CAS No. | 9004-61-9 |
| Appearance | White, fine powder |
| Assay | 95.0%~105.0% |
| Solubility | Soluble in water |
| Heavy metals | ≤10ppm |
| Protein | ≤0.1% |
| Bacterial endotoxins | ≤0.05IU/mg |
| Source | Microbial fermentation |
Key Advantages
Non-Animal Derivative: Eliminates the risk of animal-derived virus transmission, eliminates allergen concerns, and ensures higher safety.
Extremely High Purity and Low Endotoxin: Extremely low endotoxin levels significantly reduce the risk of adverse reactions such as redness and inflammation after injection.
Excellent Stability: Hyaluronic acid exhibits good thermal stability and a long shelf life, facilitating subsequent formulation processing.
Precisely Controllable Molecular Weight: Specific molecular weight ranges of hyaluronic acid can be provided according to customer needs to meet diverse clinical application requirements.
Main Application Areas
Medical Aesthetic Fillers
Hyaluronic acid is used for facial filling, wrinkle repair, and lip shaping. Its cross-linked support and biodegradation time are excellent.
Orthopedic Treatment
Hyaluronic acid acts as a synovial fluid supplement in joint cavities, relieving osteoarthritis pain and protecting articular cartilage.
Ophthalmic Surgery
Hyaluronic acid is used as a viscoelastic agent in cataract and glaucoma surgery, protecting intraocular tissues and maintaining surgical space.
Postoperative Adhesion Prevention
Hyaluronic acid is used after pelvic or abdominal surgery to form a physical barrier, effectively preventing tissue adhesion.
Production Process
Strain Selection: Non-GMO, non-pathogenic streptococci are selected for cultivation.
Controlled Fermentation: Conducted in a fully automated stainless steel fermenter, with real-time monitoring of pH, temperature, and dissolved oxygen levels.
Multi-stage Purification: Utilizing patented technologies such as chromatography, ultrafiltration, and alcohol precipitation to effectively remove proteins, nucleic acids, and microbial impurities.
Aseptic Processing: The production environment meets GMP requirements to ensure the sterility of the final product.
Packaging and Storage
· Inner Packaging: Pharmaceutical-grade low-density polyethylene bottle/bag, double-sealed.
· Outer Packaging: Aluminum foil bag or carton.
· Storage Conditions: Recommended storage at 2℃~10℃, protected from light and sealed.
· Shelf Life: Under suitable storage conditions, the shelf life is typically 24 months.